The neuroactive potential of the human gut microbiota in quality of life and depression
Valles-Colomer M, Falony G, Darzi Y, et al. · Nature Microbiology 2019
Population cohort study
Key finding
Two bacterial genera were consistently depleted in people with depression, independent of antidepressant use.
In plain language
A large population study finding a real, repeatable association between gut bacteria and depression. Association only — it cannot tell us which came first.
How much weight this carries
Real evidence exists, but it is early, limited, or not yet replicated widely.
Cite or read it
Valles-Colomer M, Falony G, Darzi Y, et al. (2019). The neuroactive potential of the human gut microbiota in quality of life and depression. Nature Microbiology. https://doi.org/10.1038/s41564-018-0337-x