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The Microbiota-Gut-Brain Axis

Cryan JF, O'Riordan KJ, Cowan CSM, et al. · Physiological Reviews 2019

Review · Open access

Key finding

Comprehensive mapping of the nerve, immune and metabolic routes between gut microbes and the brain.

In plain language

The most thorough single reference on how gut bacteria could affect the brain. Detailed on mechanism, explicit that human causal evidence is still thin.

How much weight this carries

Real evidence exists, but it is early, limited, or not yet replicated widely.

Cite or read it

Cryan JF, O'Riordan KJ, Cowan CSM, et al. (2019). The Microbiota-Gut-Brain Axis. Physiological Reviews. https://doi.org/10.1152/physrev.00018.2018

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