Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat
Kelly JR, Borre Y, O'Brien C, et al. · Journal of Psychiatric Research 2016
Animal experiment
Key finding
Rats given gut bacteria from depressed humans developed depression-like behaviour.
In plain language
One of the strongest causal signals available — but in rats. It shows the gut community can drive behaviour, without proving it does so in people.
How much weight this carries
Real evidence exists, but it is early, limited, or not yet replicated widely.
Cite or read it
Kelly JR, Borre Y, O'Brien C, et al. (2016). Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat. Journal of Psychiatric Research. https://doi.org/10.1016/j.jpsychires.2016.07.019